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This book
describes the developmental process of the
brain of the medaka fish. It aims to
understand the brain structure of
vertebrates, including humans, by taking
the brain of the medaka fish as an example
and showing its actual developmental
process. From developmental and
evolutionary viewpoints, the understanding
of the brain proceeds from simple to
complex structures. Fish retain the basic
form of vertebrates, and their brain
morphology is relatively simple.
Therefore, the fish brain is useful in
understanding the brain structure. This
book is unique for describing the entire
process of the brain development in a
specific fish. In addition, the book
introduces the readers to a new concept of
“Hourglass of Brain Morphogenesis”,
concerning the general rule of brain
morphogenesis in vertebrates. The authors
propose that the brain morphology is
highly conserved at the middle
developmental stage but diverges more
extensively at earlier and later stages.
The new concept challenges the accepted
theory that has been widely shared for
about 200 years since K. von Baer (1828,
1837) and K. von Kupffer (1906) who
proposed that three primary brain vesicles
at earlier developmental stages develop
into five secondary brain vesicles at
later developmental stages in all
vertebrates. The book provides a basic
understanding of the vertebrate brain and
is useful for all readers who wish to
understand the complex structure of the
brain.
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